Christian Roy
Northborough, Massachusetts, United States
831 followers
500+ connections
About
Experienced Computational Biologist with a demonstrated history of working in the…
Activity
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Tomorrow, join our CTO, Kim Nguyen, and other industry leaders as Women In Bio - Engage. Educate. Empower. – Greater Boston hosts the panel…
Tomorrow, join our CTO, Kim Nguyen, and other industry leaders as Women In Bio - Engage. Educate. Empower. – Greater Boston hosts the panel…
Liked by Christian Roy
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Gary Shapiro, our VP, Discovery Biology, is presenting today at the 15th Drug Discovery Strategic Summit in Boston. Come listen and learn more about…
Gary Shapiro, our VP, Discovery Biology, is presenting today at the 15th Drug Discovery Strategic Summit in Boston. Come listen and learn more about…
Liked by Christian Roy
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Really excited about attending this conference in Baltimore this week. So many precision medicine testing needs in non-oncology & in the gene & cell…
Really excited about attending this conference in Baltimore this week. So many precision medicine testing needs in non-oncology & in the gene & cell…
Liked by Christian Roy
Experience
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Education
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Activities and Societies: Sigma Alpha Epsilon
Licenses & Certifications
Publications
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Widespread haploid-biased gene expression enables sperm-level natural selection
Science
Sperm cells are genetically haploid, but because of the cytoplasmic bridges that link cells, they can be transcriptionally diploid. However, some gene transcripts are not shared. Bhutani et al. sequenced single sperm from mice, cattle, and macaques to determine the extent of distortion in the expression of these putatively selfish transcripts, which the authors call genoinformative markers (GIMs). Investigating the evolutionary pressures on these GIMs, they found that they exhibited signatures…
Sperm cells are genetically haploid, but because of the cytoplasmic bridges that link cells, they can be transcriptionally diploid. However, some gene transcripts are not shared. Bhutani et al. sequenced single sperm from mice, cattle, and macaques to determine the extent of distortion in the expression of these putatively selfish transcripts, which the authors call genoinformative markers (GIMs). Investigating the evolutionary pressures on these GIMs, they found that they exhibited signatures of positive selection yet tend to be biased toward sperm function. This observation explains why, relative to other tissues, testis shows distinctive gene expression patterns.
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Patents
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Deducing Exon Connectivity by RNA-Templated DNA Ligation/Sequencing
US 14602756
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Honors & Awards
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Poster Prize For ‘Innovation and Interdisciplinary Research’
Nature Reviews Mol. Cell Biology & The RNA Society
Languages
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English
Native or bilingual proficiency
Organizations
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RNA Society
Member
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Sigma Alpha Epislon
Member
- Present
More activity by Christian
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BRAVO to Affini-T Therapeutics' Scientific Advisory Board member Susan Kaech from Salk Institute for Biological Studies elected to the U.S. National…
BRAVO to Affini-T Therapeutics' Scientific Advisory Board member Susan Kaech from Salk Institute for Biological Studies elected to the U.S. National…
Liked by Christian Roy
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Next week, CAMP4 VP of Platform Alla Sigova will present on our unique approach to amplifying RNA at the American Society of Gene & Cell Therapy’s…
Next week, CAMP4 VP of Platform Alla Sigova will present on our unique approach to amplifying RNA at the American Society of Gene & Cell Therapy’s…
Liked by Christian Roy
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Connect with us and learn about our latest advancements in #cancer research and #Tcell therapies targeting #tp53 and #KRAS mutations at the American…
Connect with us and learn about our latest advancements in #cancer research and #Tcell therapies targeting #tp53 and #KRAS mutations at the American…
Liked by Christian Roy
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Congratulations to Google DeepMind Google Research and the entire team on releasing this new family of multimodal for medicine , unlocking exciting…
Congratulations to Google DeepMind Google Research and the entire team on releasing this new family of multimodal for medicine , unlocking exciting…
Liked by Christian Roy
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Exciting news! Thrilled to announce that Thaminda Ramanayake will strengthen the CureVac team as our Chief Business Officer starting in June! 🎉 With…
Exciting news! Thrilled to announce that Thaminda Ramanayake will strengthen the CureVac team as our Chief Business Officer starting in June! 🎉 With…
Liked by Christian Roy
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I'm very excited to be co-organizing the FASEB meeting on mechanisms of RNA decay, which will take place in Lisbon August 18th-22nd. If you are…
I'm very excited to be co-organizing the FASEB meeting on mechanisms of RNA decay, which will take place in Lisbon August 18th-22nd. If you are…
Liked by Christian Roy
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#DYK: Despite ADCs being specifically designed to deliver chemotherapy directly to #tumors, over 95% of any given dose is not taken up by the tumor…
#DYK: Despite ADCs being specifically designed to deliver chemotherapy directly to #tumors, over 95% of any given dose is not taken up by the tumor…
Liked by Christian Roy
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Many thanks to Michael Caligiuri, Christiana Bardon, and William Hait for the invitation to speak at the "Inaugural AACR Oncology Industry…
Many thanks to Michael Caligiuri, Christiana Bardon, and William Hait for the invitation to speak at the "Inaugural AACR Oncology Industry…
Liked by Christian Roy
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Hi network, thanks a lot for your support over these last weeks! I'm thrilled to announce that I accepted an offer for a really exciting role 🥳. I…
Hi network, thanks a lot for your support over these last weeks! I'm thrilled to announce that I accepted an offer for a really exciting role 🥳. I…
Liked by Christian Roy
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Google Cloud Next in LV was an absolute blast! Huge congrats to our incredible startups, and a massive shout-out to the Canadian healthcare & life…
Google Cloud Next in LV was an absolute blast! Huge congrats to our incredible startups, and a massive shout-out to the Canadian healthcare & life…
Liked by Christian Roy
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Great to host Wugen at NMDP world headquarters today. NK cells are Natural Killers of cancer. We are proud to work with them to find creative ways…
Great to host Wugen at NMDP world headquarters today. NK cells are Natural Killers of cancer. We are proud to work with them to find creative ways…
Liked by Christian Roy
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Absolutely fantastic recognition for the work done by Lydeard et al. Worth a read. Congratulations John Lydeard and team!
Absolutely fantastic recognition for the work done by Lydeard et al. Worth a read. Congratulations John Lydeard and team!
Liked by Christian Roy
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On #RareDiseaseDay, Terence R. Flotte, MD, told members of Congress that costs and logistics associated with product development remain barriers to…
On #RareDiseaseDay, Terence R. Flotte, MD, told members of Congress that costs and logistics associated with product development remain barriers to…
Liked by Christian Roy
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Today marks an important step toward our commitment to harnessing the power of cell therapy in autoimmune disease. @Nasdaq, #IPO trading as #$KYTX…
Today marks an important step toward our commitment to harnessing the power of cell therapy in autoimmune disease. @Nasdaq, #IPO trading as #$KYTX…
Liked by Christian Roy
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Thank you to Christopher Ghadban for taking the time to connect with our Chief Scientific Officer and Co-Founder, Brian Fiske, PhD, for an episode on…
Thank you to Christopher Ghadban for taking the time to connect with our Chief Scientific Officer and Co-Founder, Brian Fiske, PhD, for an episode on…
Liked by Christian Roy
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